Skip to content

Lung Cancer Blog

Everything about lung cancer is here.

Menu
  • Home
  • About Us
  • Lung Cancer
    • Lung Cancer News
    • Causes of Lung Cancer
    • Lung Cancer Symptoms
    • Types of Lung Cancer
    • Stages of Lung Cancer
    • Lung Cancer Treatment
    • Lung Cancer Drugs
    • Lung Cancer In Ayurveda
    • Chinese Herbs For Lung Cancer
  • Researches
  • Studies
  • Stories
  • Sitemap
  • Contact Us
Menu
Skeletal Model of Topotecan | Lung Cancer

Topotecan–Berzosertib Combination Effective for SCLC Treatment

Posted on May 10, 2021
Post Views: 354

Skeletal Model of Topotecan | Lung Cancer | SCLCResearchers all over the world are continuously been working towards finding effective treatments and therapies for lung cancer. There are widely two types of lung cancer: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Most patients suffering from SCLC initially respond to chemotherapy or immunotherapy but usually, the cancer comes back. They then are not able to respond to additional treatment. The current treatment options for patients with SCLC are limited. The researchers have identified a new combination of two drugs that can work to shrink the tumors of patients with SCLC.

The new combination includes chemotherapy drug Topotecan and Berzosertib. While Topotecan is FD approved for some patients with SCLC and Berzosertib is an investigational drug which inhibits a protein to help in repairing damaged DNA. This combination therapy worked out to shrank tumors in 9 out of 25 SCLC patients in the NCL-supported clinical trial. The results were published in Cancer Cell. Encouraged by these results, they expanded the trial to study patients whose small cell lung cancers originated outside the lungs. Three out of 10 patients’ tumors shrank in response of the treatment.

Topotecan | Lung Cancer |  | Lung Cancer“We were quite surprised by the responses of patients whose cancers had developed resistance to chemotherapy,” said lead researcher Anish Thomas, M.D., of NCI’s Center for Cancer Research. “Learning that these patients could stay on the combination therapy for months was the most exciting finding of the study,” he added.  He says that these new findings could pave the way for more personalized treatment for patients with SCLC. A separate clinical trial will evaluate the combination therapy’s effects, specifically in patients whose SCLCs are resistant to platinum-based chemotherapy and it will be sponsored by the EMD Serono Research & Development Institute.

 

The information shared in this blog is for educational purposes only. Subscribe to our newsletter for latest updates.

 

Subscribe to our newsletter or follow us on Facebook or Twitter today and never miss out an update!

  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X
  • Click to share on Pinterest (Opens in new window) Pinterest
  • Click to share on Threads (Opens in new window) Threads
  • Click to share on WhatsApp (Opens in new window) WhatsApp
  • Click to share on Reddit (Opens in new window) Reddit
  • Click to share on Tumblr (Opens in new window) Tumblr
  • Click to share on Pocket (Opens in new window) Pocket
  • Click to share on Telegram (Opens in new window) Telegram

Like this:

Like Loading...

Subscribe Us

Popular Articles

  • Lung Cancer Treatment in Ayurveda (7,322)
  • Lung Cancer: Symptoms and Treatment (5,655)
  • What is Non-Small-Cell Lung Cancer? (5,551)

Recent Comments

  • Lung Cancer on New Study To Help Advance Research In Lung Cancer
  • Laurie B Grimes on New Study To Help Advance Research In Lung Cancer
  • Lung Cancer on Asbestos and Lung Cancer – What’s The Link?

Recent Articles

  • Study: Wildfire Smoke Exposure Affects Lung Cancer Survival June 2, 2025
  • Predicting Lung Cancer Risk with AI based Deep Learning Model May 26, 2025
  • FDA Grants Accelerated Approval to Telisotuzumab Vedotin-tllv for NSCLC May 19, 2025
  • Heart-Sparing Technique in Lung Cancer Radiotherapy May 12, 2025
  • Origins of Common Lung Cancer Linked to Smoking Discovered May 5, 2025

Lung Cancer Blog

Lung Cancer Blog provides all lung cancer related information for educational purposes.

Disclaimer

Some post may contain affiliate links, purchasing that product not going to cost extra but by your purchase Lung Cancer will get some little commission and that amount will help in surviving this website. So, please don’t hesitate to buy from these affiliate links.

Contact Us

If you have any query or suggestions about our blog, please feel free to email us at  lungcancersymptomsx@gmail.com.

Copyright © 2012 - 2025 Lung Cancer Blog. Wordpress by Vipasha.
  • Privacy Policy
  • About Us
  • Sitemap
  • Contact Us
%d