Skip to content

Lung Cancer Blog

Everything about lung cancer is here.

Menu
  • Home
  • About Us
  • Lung Cancer
    • Lung Cancer News
    • Causes of Lung Cancer
    • Lung Cancer Symptoms
    • Types of Lung Cancer
    • Stages of Lung Cancer
    • Lung Cancer Treatment
    • Lung Cancer Drugs
    • Lung Cancer In Ayurveda
    • Chinese Herbs For Lung Cancer
  • Researches
  • Studies
  • Stories
  • Sitemap
  • Contact Us
Menu
Non-Smoker's Lung Cancer

NIH Study Uncovers Causes of Lung Cancer among Non Smokers

Posted on September 13, 2021
Post Views: 427

Non-Smoker's Lung Cancer

A new study has been conducted by an international team led by researchers at the US National Cancer Institute (NCI), part of the National Institutes of Health (NIH). The findings were published in Nature Genetics, describing three molecular subtypes of lung cancer in people who have never smoked. The analysis done in people with no history of smoking has found that majority of tumors arise from accumulation of mutations caused by natural processes.

In this study; the researchers used whole-genome sequencing to find the genomic changes in tumor tissues and then matched normal tissue with 232 never smokers. The tumors included 189 adenocarcinomas, 36 carcinoids and 7 other tumors of different types. These never smokers had been diagnosed with non-small cell lung cancer but had not yet undergone any treatment. The researchers combed the tumor genomes for mutational signatures like damage from natural activities in the body. The team has discovered that majority of tumor genomes of these lung cancer patients bore mutational signatures associated with damage from endogenous processes.

‘We’re at the beginning of understanding how these tumors evolve,’ Dr Maria Teresa Landi said. ‘This analysis shows that there is heterogeneity, or diversity, in lung cancers in never smokers.’ The study was limited to only those people who are non smokers and thus, the researchers did not find any mutational signatures that have previously been associated with direct exposure to smoking. Also, they did not find those signatures among 62 patients who had been exposed to second-hand tobacco smoke.

Considering the limitations of the study, more research is required to be done to classify different lung cancer subtypes and then develop treatments for those who have never smoked.

The information shared in this blog is for educational purposes only and is certainly not a substitute for medical advice. It is advised to consult your healthcare practitioner for any health issues.

Subscribe to our newsletter or follow us on Twitter or Facebook today and never miss an update!flung

  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X
  • Click to share on Pinterest (Opens in new window) Pinterest
  • Click to share on Threads (Opens in new window) Threads
  • Click to share on WhatsApp (Opens in new window) WhatsApp
  • Click to share on Reddit (Opens in new window) Reddit
  • Click to share on Tumblr (Opens in new window) Tumblr
  • Click to share on Pocket (Opens in new window) Pocket
  • Click to share on Telegram (Opens in new window) Telegram

Like this:

Like Loading...

Subscribe Us

Popular Articles

  • Lung Cancer Treatment in Ayurveda (7,325)
  • Lung Cancer: Symptoms and Treatment (5,657)
  • What is Non-Small-Cell Lung Cancer? (5,552)

Recent Comments

  • Lung Cancer on New Study To Help Advance Research In Lung Cancer
  • Laurie B Grimes on New Study To Help Advance Research In Lung Cancer
  • Lung Cancer on Asbestos and Lung Cancer – What’s The Link?

Recent Articles

  • Study: Wildfire Smoke Exposure Affects Lung Cancer Survival June 2, 2025
  • Predicting Lung Cancer Risk with AI based Deep Learning Model May 26, 2025
  • FDA Grants Accelerated Approval to Telisotuzumab Vedotin-tllv for NSCLC May 19, 2025
  • Heart-Sparing Technique in Lung Cancer Radiotherapy May 12, 2025
  • Origins of Common Lung Cancer Linked to Smoking Discovered May 5, 2025

Lung Cancer Blog

Lung Cancer Blog provides all lung cancer related information for educational purposes.

Disclaimer

Some post may contain affiliate links, purchasing that product not going to cost extra but by your purchase Lung Cancer will get some little commission and that amount will help in surviving this website. So, please don’t hesitate to buy from these affiliate links.

Contact Us

If you have any query or suggestions about our blog, please feel free to email us at  lungcancersymptomsx@gmail.com.

Copyright © 2012 - 2025 Lung Cancer Blog. Wordpress by Vipasha.
  • Privacy Policy
  • About Us
  • Sitemap
  • Contact Us
%d