Drug: Vinorelbine (Navelbine) to treat NSCLC

Vinorelbine (Navelbine)Vinorelbine, a chemotherapy drug, is sold under the trade name of Navelbine to treat various types of cancer. It has been approved for treatment of non-small-cell lung cancer and works in damaging cancer cells. It helps to block the cancer growth by stopping the cancer cells from separating into two new cells. It is an active therapeutic option for treatment of early as well as advanced NSCLC.


How is it given?

Vinorelbine is usually given through a vein by intravenous injection or infusion. Your nurse will give you it as a drip into your cannula between 5-10 minutes.  Vinorelbine capsules are also given to the patients in form of 20mg, 30mg and 80mg. The patients will swallow them with water and do not chew or suck them. Your doctor or nurse will determine the dosage and course of treatment. It is generally given on days 1 and 8 every 3 weeks. It is the third-generation drug that has shown consistent improvement in survival on a long-term basis.


Side Effects

We have listed the side effects associated with Vinorelbine. You may or may not experience this. They may be mild or more severe. The side effects depend on your general health and the dosage of the drug. The side effects may be different when you are taking this drug with other medicines.


Common Side Effects

  • Drop in red blood cells resulting in tiredness and breathlessness
  • Constipation can be an issue
  • Muscle weakness or vomiting
  • Feeling or being sick
  • Hair loss
  • Temporary numbness and tingling
  • Loss or appetite
  • Sore mouth


Important Tips

  • Tell your doctor about any other medicines you are taking
  • Talk to your doctor about the side effects you are facing
  • You should not breastfeed during the treatment
  • Talk to your doctor about effective contraception before the treatment begins


Vinorelbine has shown to be an effective agent among patients with advanced disease. As the treatment of NSCLC becomes personalized, the role of Vinorelbine varies from person to person. But, it remains a vital agent in the treatment of NSCLC based on its tolerability.


All information provided in this blog is for educational purposes only and is not a substitute for medical advice.

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