Skip to content

Lung Cancer Blog

Everything about lung cancer is here.

Menu
  • Home
  • About Us
  • Lung Cancer
    • Lung Cancer News
    • Causes of Lung Cancer
    • Lung Cancer Symptoms
    • Types of Lung Cancer
    • Stages of Lung Cancer
    • Lung Cancer Treatment
    • Lung Cancer Drugs
    • Lung Cancer In Ayurveda
    • Chinese Herbs For Lung Cancer
  • Researches
  • Studies
  • Stories
  • Sitemap
  • Contact Us
Menu
Non-Small-Cell Lung Cancer (NSCLC)

Detecting Circulating Tumor Cells in Non-Small Cell Lung Cancer Patients

Posted on March 15, 2021
Post Views: 425

Non-Small-Cell Lung Cancer (NSCLC)Non-small cell lung cancer is the most prevalent form of lung cancer and accounts for more than 80% of all lung cancer cases. Circulating tumor cells (CTCs) lead to metastases and often goes undetected in blood and now, scientists have developed a novel method to better detect CTCs. The research was published in the journal Proceedings of the National Academy of Sciences. The team of researchers looked at hexokinase-2 or HK2, a key enzyme in glucose metabolism.

Institute for Systems Biology (ISB) is a collaborative non-profit biomedical research organization. ISB Assistant Professor, Dr. Wei Wei, said, “A set of previous reports from our collaborator Dr. Herschman (co-author of the paper) and others revealed that cancer cells often rely on HK2 to elevate glucose metabolism to fuel their uncontrolled growth, making this enzyme a desirable target for testing.”

The various techniques of CTC identifications are split into blood groups according to methods of cell enrichment and cell detection. The conventional CTC detection methods normally rely on use of family of proteins called cytokeratins, found in epithelial tissues. Despite highly aggressive nature of non-small cell lung cancer, their performance in NSCLC is sub-optimal. The researchers worked to address this issue and achieve a greater spectrum for CTC detection by exploiting a common feature of wide range of cancer cells. The use of HK2 as a biomarker leads to developing metabolic activity-based methods for identification of novel CTC population without CK expression. The use of HK2 as a tumor cell marker allows revealing a novel circulating tumor cell population which is normally overlooked by current epithelial marker-based CTC detection methods.

Wei said, “This approach can be exploited to anticipate NSCLC patient therapy response before they undergo cancer therapy, and more generally, it will be useful in identifying CTCs from patients with a wide variety of cancers, independent of epithelial traits.”

 

The information shared in this blog is for educational purposes only. Subscribe to our newsletter for receiving latest news right in your inbox.

 

For regular updates follow us on Facebook or Twitter.

  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X
  • Click to share on Pinterest (Opens in new window) Pinterest
  • Click to share on Threads (Opens in new window) Threads
  • Click to share on WhatsApp (Opens in new window) WhatsApp
  • Click to share on Reddit (Opens in new window) Reddit
  • Click to share on Tumblr (Opens in new window) Tumblr
  • Click to share on Pocket (Opens in new window) Pocket
  • Click to share on Telegram (Opens in new window) Telegram

Like this:

Like Loading...

Subscribe Us

Popular Articles

  • Lung Cancer Treatment in Ayurveda (7,325)
  • Lung Cancer: Symptoms and Treatment (5,657)
  • What is Non-Small-Cell Lung Cancer? (5,552)

Recent Comments

  • Lung Cancer on New Study To Help Advance Research In Lung Cancer
  • Laurie B Grimes on New Study To Help Advance Research In Lung Cancer
  • Lung Cancer on Asbestos and Lung Cancer – What’s The Link?

Recent Articles

  • Study: Wildfire Smoke Exposure Affects Lung Cancer Survival June 2, 2025
  • Predicting Lung Cancer Risk with AI based Deep Learning Model May 26, 2025
  • FDA Grants Accelerated Approval to Telisotuzumab Vedotin-tllv for NSCLC May 19, 2025
  • Heart-Sparing Technique in Lung Cancer Radiotherapy May 12, 2025
  • Origins of Common Lung Cancer Linked to Smoking Discovered May 5, 2025

Lung Cancer Blog

Lung Cancer Blog provides all lung cancer related information for educational purposes.

Disclaimer

Some post may contain affiliate links, purchasing that product not going to cost extra but by your purchase Lung Cancer will get some little commission and that amount will help in surviving this website. So, please don’t hesitate to buy from these affiliate links.

Contact Us

If you have any query or suggestions about our blog, please feel free to email us at  lungcancersymptomsx@gmail.com.

Copyright © 2012 - 2025 Lung Cancer Blog. Wordpress by Vipasha.
  • Privacy Policy
  • About Us
  • Sitemap
  • Contact Us
%d